Piperazine based cytofectins

Details Piperazine based cytofectins Piperazine based cytofectins

1998-12-23

2000-02-08

LeGuyader, John L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514247, 514255, 424 121, 424417, 424420, 424812, 424 9321, 427 214, 544358, 544359, A01N 4358, A01N 2526, A61K 3900

Patent

active

060228741

ABSTRACT:
The present invention relates to piperazine based amphilic cationic lipids useful for gene therapy, transfection, and introducing immunogenic compounds for the purpose of vaccination. The disclosed compounds have lipophilic moieties linked to the ring nitrogens. In addition, at least one of the ring nitrogens is quatranized and linked to a hydrocarbon having at least one heteroatom.

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