Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2006-10-03
2006-10-03
Thompson, Jewel (Department: 2855)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
83, C073S861000
Reexamination Certificate
active
07115399
ABSTRACT:
Method for measuring potency of a substance, the method including; administering the substance to a mammal; subjecting the mammal to a stimulus; and monitoring a pinna reflex response of the mammal.
REFERENCES:
patent: 4065561 (1977-12-01), Gassel
patent: 4407232 (1983-10-01), Konz
patent: 4607040 (1986-08-01), Pearce et al.
patent: 5053005 (1991-10-01), Borodic
patent: 5435999 (1995-07-01), Austin
patent: 5562907 (1996-10-01), Arnon
patent: 5814488 (1998-09-01), Zhao et al.
patent: 6087327 (2000-07-01), Pearce et al.
patent: 6316434 (2001-11-01), Robichaud et al.
patent: 6358926 (2002-03-01), Donovan
patent: 6461617 (2002-10-01), Shone et al.
patent: 6500436 (2002-12-01), Donovan
patent: 6514685 (2003-02-01), Moro
patent: 6545126 (2003-04-01), Johnson et al.
patent: 6597944 (2003-07-01), Hadas
patent: 6632977 (2003-10-01), Kieffer et al.
Adenis, J. P., et al.,Traitement des spasms faciaux par la toxine botulique A., J Fr Ophthalmol 1990;13(5) pp. 259-264.
Angaut-Petit, D., et al.,The levator auris longus muscle of the mouse: a convenient preparation for studies of short-and long-term presynaptic effects of drugs or toxins, Neuroscience Letters 82(1987) 83-88.
Blitzer, A., et al.,Electromyographic findings in focal laryngeal dystonia(spastic dysphonia), Ann Otol Rhinol Laryngol 94:1985 pp. 591-594.
Brin, M.F, et al.,Localized injections of botulinum toxin for treatment of focal dystonia and hemifacial spasm, Advances in Neurology, vol. 50, Dystonia 2, NY Raven Press 1988 pp. 599-608.
Casella, J.V., et al.,Habituation, prepulse inhibition, fear conditioning, and drug modulatonof the acoustically elicited pinna reflex in rats, Bahavioral Neuroscience, 1986, vol. 100, No. 1, 39-44.
Caser, M., et al.,Startle repsonses measured in muscles innervated by facial and trigeminal nerves show common modulation, Behavioral Neuroscience, 1989, vol. 103, No. 5, pp. 1075-1081.
Cohen, L., et al.,Treatment of focal dystonias of the hand with botulinum toxin injection, Neurology Mar 1987 37(Suppl 1): 123-4.
Elston, J.S. , et al.,Paralytic strabismus: the role of botulinum toxin, Br J. Ophthalmol Dec. 1985; 69(12):891-6.
Hambleton, R.,Clostridium botulinum toxins: a general review of involvement in disease, structure, mode of action and preparation for clinical use, J. Neurol 1992 239:16-20.
Hatheway, C.L., Simpson, L.L., Ed., Academic Press Inc., 1989, Botulinum Neurotoxin and tetanus toxin, Chp. 1,Bacterial Sources of clostridial neurotoxins, pp. 3-24.
Jankovic, J., et al.,Therapeutic uses of botulinum toxin,, N. Engl J Med Apr. 1991;324(17):1186-1194.
Jankovic, J., et al.,Botulinum A toxin for cranial-cervical dystonia, Neurology 1987;37(4):616-23.
Juzans, P., et al.,Nerve Terminal sprouting in botulinum type-A treated mouse levator auris longus muscle, Neuromusc. Disord, vol. 6, No. 3, pp. 177-185, 1996.
Pearce, L.B., et al.,Measurement of botulinum toxin activity: evaluation of the lethality assay, Toxicology and applied Pharmacology 128,69-77 (1994).
Pilz, P.K., et al.,Comparative Threshold Studies of the Acoustic Pinna, Jaw and Startle Reflex in the Rat, Physiology & Behavior, 1988, vol. 43, pp. 44-415.
Schantz, E. J., et al.,Microbiological Methods Standardized assay for clostridium botulinum toxins, J. Assoc Off Anal Chem, 1978;61(1):96-9.
Schantz, E.J., et al.,Properties and use of botulinum toxin and other microbial neurotoxins in medicine, Microbiol Rev Mar. 1992; 56(1):80-99.
Sesardic, D., et al.,Refinement and validation of an alternative bioassy for potency testing of therapeutic botulinum type A toxin, Pharmacology & Toxicology 1996, 78(5) 283-288.
Allergan Inc.
Barran Robert J.
Donovan Stephen
Thompson Jewel
Voet Martin A.
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