Pinitol and derivatives thereof for the treatment of metabolic d

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai

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A61K 31075

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active

058278966

ABSTRACT:
Pinitol and derivatives and metabolites thereof are useful in nutritional and medicinal compositions for lowering plasma free fatty acid levels and for treating conditions associated with insulin resistance, such as diabetes mellitus and its chronic complications; obesity; hyperlipidemias and dyslipidemias atherosclerosis; hypertension; cardiovascular disease; AIDS; cancer; wasting/cachexia; sepsis; trauma associated with burns, malnutrition, and stress; aging; lupus and other autoimmune diseases; endocrine disease; hyperuricemia, polycystic ovary syndrome and complications arising from athletic activity.

REFERENCES:
patent: 5550166 (1996-08-01), Ostlund et al.
"Hypoglycaemic Plants--A Review", Handa, S.S., et al., Fitoterapia, vol. 60, No. 3, (1989), pp. 195-224.
"Pinitol-A New Anti-Diabetic Compound From the Leaves of Bougainvillea Spectabilis", Narayanan, et al., Current Science, vol. 56, No. 3, (1987), pp. 139-141.
"Preferential Leaching of Pinitol from Soybeans During Imbibition", Philip Nordin, Plant Physiol., vol. 76, No. 2, (1984), pp. 313-315.
"Cyclitols in Soybean", Phillips, et al., Agric. Food Chem., vol. 30, No. 1, (1982).

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