Pinene derivatives and pharmaceutical compositions containing th

Details Pinene derivatives and pharmaceutical compositions containing th Pinene derivatives and pharmaceutical compositions containing th

1979-07-23

1981-08-04

Mars, Howard T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424346, 560141, 560255, 568734, A61K 3122, A61K 3105, C07C 69013, C07C 3917

Patent

active

042822483

ABSTRACT:
The present invention relates to novel compounds of the general formula ##STR1## wherein R.sup.1 is --H or --CO--alk, wherein alk is lower alkyl of 1 to 5 carbon atoms; R.sup.2 is 1,1-dimethylheptyl or 1,2-dimethylheptyl, Q is --CH.sub.3 when A------B is a single bond, and Q is --CH.sub.2 OR.sup.4 when A------B is a double bond, and R.sup.4 is --H or --CO--alk where alk is lower alkyl of 1 to inclusive 5 carbon atoms.
The invention relates both to the isomeric mixtures and to the individual isomers of the above compounds. Furthermore the invention relates to pharmaceutical compositions containing a compound defined above as active ingredient. The pharmaceutical compositions are of value as central nervous system depressants, as sedatives, as tranquilizers, as anticonvulsant agents, as effective agents against migraine, for the treatment of glaucoma, as antidiarrheal agents and as antiinflammatory agents. The invention also relates to a process for the production of the above compounds and pharmaceutical compositions.

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