Pinacidil-diuretic preparation for treating hypertension or cong

Details Pinacidil-diuretic preparation for treating hypertension or cong Pinacidil-diuretic preparation for treating hypertension or cong

1982-03-31

1983-10-11

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424263, A61K 31505, A61K 3144

Patent

active

044092229

ABSTRACT:
The present invention relates to a pharmaceutical preparation containing as the vasodilator N"-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine and as the diuretic active component a compound selected from the group consisting of the thiazide or thiazide-like type diuretics and loop diuretics.
The combination is valuable in the treatment of mammals, including man, suffering e.g. from hypertension or congestive heart failure.

REFERENCES:
patent: 4057636 (1977-11-01), Petersen
Petersen, H. et al., J. Med. Chem., 21(8), 773-781 (1978).
Arrigoni-Martelli, E. et al., Experientia, 36, 445-447 (1980).
International Nonproprietary Names for Pharmaceutical Substances, Cumulative List 6, WHO, Geneva, 1982, p. 244.
Chemical Abstracts Registry Handbook, 1976 Supplement, p. 2011 Re.

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