Pigment epithelial cell of the eye, its production and use...

Details Pigment epithelial cell of the eye, its production and use... Pigment epithelial cell of the eye, its production and use...

2007-07-24

2007-07-24

Whiteman, Brian (Department: 1635)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of co-culturing cells

C435S455000

Reexamination Certificate

active

10079609

ABSTRACT:
The present invention relates to a pigment epithelial cell of the eye containing vector DNA of an adenoviral vector with large DNA capacity, to the improved isolation and cultivation of these cells and to methods for production and the use in the therapy of an eye or nerve disease.

REFERENCES:
patent: 6667176 (2003-12-01), Funk et al.
patent: 2003/0045498 (2003-03-01), Kovesdi et al.
U.S. Appl. No. 60/228,337.
Tezel et al., Exp. Eye Res. 66, 807-815, 1998.
Williams et al., Nature. Dec. 15, 1988;336(6200):684-7.
Morsy et al. PNAS, vol. 95, 7866-7871, 1998.
Anglade et al., “Recombinant Adenovirus-Mediated Gene Transfer Into the Adult Rat Retina,”Current Eye Research17:316-321 (1998).
Kumar-Singh et al., “Encapsidated Adenovirus Minichromosomes Allow Delivery and Expression of a 14 kb Dystrophin cDNA to Muscle Cells,”Human Molecular Genetics5:913-921 (1996).
Li et al., “In Vivo Transfer of a Reporter Gene to the Retina Mediated by an Adenoviral Vector,”Investigative Ophthalmology&Visual Science35:2543-2549 (1994).
Rakoczy et al., “Recombinant Adenovirus-Mediated Gene Delivery Into the Rat retinal Pigment Epithelium in vivo,”Australian and New Zealand Journal of Ophthalmology26:S56-S58 (1998).
Baffi et al., “Evaluation of Second Generation Adenoviral Vectors for Gene Delivery into Retinal Pigment Epithelial Cells”IOVS., 39(4):S719, Abstract 3302-B128,1998.
Reichel et al., “Gene Transfer in Ophthalmology,”Ophtalmologe, 96(9):570-577, 1999, with English translation.

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