Piezoelectric cell growth biosensing method using polymer-metabo

Details Piezoelectric cell growth biosensing method using polymer-metabo Piezoelectric cell growth biosensing method using polymer-metabo

1989-07-25

1992-08-04

Lacey, David L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 34, 436501, 436806, 436908, C12Q 104, C12Q 106, G01N 33566

Patent

active

051358522

ABSTRACT:
The invention relates to a piezoelectric biosensor device and also to a method and a system utilizing a piezoelectric biosensor device for detecting metabolic growth requirements, antibiotic responses, and the specific bacterial products of microorganisms. When a microorganism is grown in an appropriate nutrient medium containing a metabolic product responsive polymer, metabolic products of the organism acidify the medium and precipitate a polymer metabolic product complex which deposits or accumulates on the surface of a piezoelectric biosensor device. The mass change on the surface of the device resulting from this deposit produces a change in the resonant frequency of the piezoelectric biosensor device which can be used to determine the growth and type of microorganism.

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