Pierceable pharmaceutical container closure with check valve

Details Pierceable pharmaceutical container closure with check valve Pierceable pharmaceutical container closure with check valve

1993-04-14

1994-08-02

Green, Randall L.

Surgery

Container for blood or body treating material, or means used...

Container with piercable closure

604403, 604407, 604905, 604324, A61B 1900, A61M 532

Patent

active

053341783

ABSTRACT:
A pharmaceutical container comprises a housing with a wall structure and bottom defining an inner volume, a pierceable diaphragm sealingly positioned within an opening in the housing, and a protective cover received over the diaphragm. The diaphragm has at least one fluid check valve integrally formed therein and affording one way fluid communication from ambient toward the inner volume of the housing when the fluid pressure inside the container is less than ambient. The protective cover has one or more openings in fluid communication with the diaphragm check valves either via a set of grooves formed in the upper surface of the diaphragm or through a path provided by a spacer positioned between the cover and the diaphragm. A tear away seal covers the holes in the cover to prevent air flow toward the check valves prior to initial use. When the diaphragm is pierced by a syringe needle and the syringe plunger is withdrawn, air flows from ambient through the check valves into the inner volume of the container, thereby preventing suction on the liquid flowing through the needle into the syringe.

REFERENCES:
patent: 2851201 (1958-09-01), Poitras et al.
patent: 4863453 (1989-09-01), Berger et al.
patent: 5067948 (1991-11-01), Haber et al.
patent: 5188628 (1993-02-01), Rani et al.

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