Pichia pastoris argininosuccinate lyase gene and uses thereof

Details Pichia pastoris argininosuccinate lyase gene and uses thereof Pichia pastoris argininosuccinate lyase gene and uses thereof

1985-10-25

1989-04-04

Teskin, Robin

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435232, 435849, 435255, 435938, 435320, 435 91, 4351725, 536 27, 935 14, 935 28, 935 60, 935 64, 935 73, C12N 120, C12N 988, C12N 116, C07H 1512

Patent

active

048187003

ABSTRACT:
Novel DNA sequences which code for the production of the Pichia protein argininosuccinate lyase are provided. Novel constructs including these sequences, as well as organisms transformed therewith are provided. In addition, novel strains of Pichia defective in argninosuccinate lyase activity are also provided.

REFERENCES:
patent: 4617274 (1926-10-01), Wegner
Kunze et al, Curr. Genet, vol. 9(3) Mar. 1985, pp. 205-209, "Transformation of Candida Maltosa and Pichid guillermoandii by a Plasmid Containing Saccharomyces".
Stinchomb et al., Proc. Natl. Acad. Si. vol. 77 (8) Aug. 1980, pp. 4559-4563, "Eukaryotic DNA Segments Capable of Autonomous Replication in Yeast".
Broach et al, Gene, vol. 8, 1979 pp. 121-133, "Transformation in Yeast: Development of a Hybrid Cloning Vector and Isolation of the Carl Gene".
Driscoll Renn et al, Proc. Natl. Acad. Sci., vol. 80, pp. 270-278 May 1983 "Identiication of AAS Genes and Their Regulatory Role in General Control to Amino Acid Biosynthesion Yeast".
Messenguy et al, Mol Gen Genet, 1983, vol. 189, pp. 148-156, "Participation of Transcriptional and Post-Transcriptional Regulatory Mechanisms in the Control . . . ".
Gene, vol. 29, I. R. Beacham et al, pp. 271-279 (1984).

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