Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1990-12-14
1993-12-07
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 699, 435196, 435215, 43525423, 435 19, 4353201, 435938, 536 2374, 536 241, 935 10, 935 28, 935 37, 935 69, C12N 1555, C12N 119, C12N 1581, C12P 2102
Patent
active
052682730
ABSTRACT:
The present invention discloses the Pichia pastoris acid phospbatase gene, which includes the 5' regulatory region, signal sequence, structural gene, and 3' transcription termination sequence. Also disclosed are methods of using these fragments, which include but are not limited to the secretion of proteins from cells and the regulation of the transcription of DNA. DNA vectors containing the acid phospbatase gene or fragments thereof and hosts transformed with these vectors are also disclosed. Additionally, integrative vectors which direct integration at the Pichia pastoris PHO1 locus and a method of identifying these disruptants is disclosed.
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Phillips Petroleum Company
Walsh Stephen
Wax Robert A.
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