Pichia methanolica secretory signal

Details Pichia methanolica secretory signal Pichia methanolica secretory signal

2005-09-13

2005-09-13

Wax, Robert A. (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

C530S300000

Reexamination Certificate

active

06943234

ABSTRACT:
NovelPichia methanolicasecretory signal polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods of using are disclosed. Methods of producing large amounts of recombinant proteins by employing DNA constructs having a polypeptide of interest preceded by a novelPichia methanolicasecretory signal sequence.

REFERENCES:
patent: 0495208 (1992-07-01), None
patent: 99/07862 (1999-02-01), None
Anonymous, “Secondary Antibodies and Conjugates,” Calbriochem Antibody Source Book, pp. 62-65, 2004, XP002315000.
Raymond et al., “Development of the Methylotrophic YeastPichia methanolicafor the Expression of the 65 Kilodalton Isoform of Human Glutamate Decarboxylase,”Yeast 14:11-23, 1998.

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