Physiologically active substances

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S450000, C549S271000, C544S374000

Reexamination Certificate

active

07893068

ABSTRACT:
The present invention relates to a compound represented by the formula (I):(wherein, R3, R6, R7and R21are the same as or different from one another and each represents a hydroxyl group etc.), a pharmacologically acceptable salt thereof or a hydrate of them. The compound (I) of the present invention suppresses angiogenesis, in particular, suppresses VEGF production in a hypoxic condition and is useful as a therapeutic agent for treating solid cancer.

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