Physiologically active peptide composition for nasal administrat

Details Physiologically active peptide composition for nasal administrat Physiologically active peptide composition for nasal administrat

1988-07-19

1991-10-22

Moezie, F. T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514947, 514951, 514970, 514953, A61K 3702

Patent

active

050595873

ABSTRACT:
A nasal administration powder composition containing a physiologically active peptide as an active ingredient can be efficiently absorbed through nasal mucosa by the addition of a water-soluble organic acid as an absorption promoter. This composition may further contain a diluent. The water-soluble organic acid used as absorption promoter includes, for example, at least one of succinic acid, tartaric acid, citric acid, fumaric acid, maleic acid, malonic acid, glutaric acid, adipic acid, malic acid, L-glutamic acid, L-aspartic acid, gluconic acid and glucuronic acid.

REFERENCES:
patent: 4476116 (1984-10-01), Anik
patent: 4609640 (1986-09-01), Morishita
patent: 4690952 (1987-09-01), Kagatani

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