Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-06-20
2006-06-20
Pak, Michael (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07064181
ABSTRACT:
The present invention relates to a peptide comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 35 and having an ability of binding to a receptor protein comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3, or a precursor thereof, its amide or ester, or a salt thereof.An inventive peptide-encoding DNA or equivalent can be employed in (1) a development of a receptor binding assay system using an expression system of a recombinant receptor protein and a screening for a pharmaceutical candidate compound, and (2) a development of a pharmaceutical having a reduced side effect such as a memory function improving agent, a appetite improving agent, an uterine, renal, prostatic, testicular or skeletal muscle function regulating agent.
REFERENCES:
patent: 5576296 (1996-11-01), Bartfai et al.
patent: WO 92/12997 (1992-08-01), None
patent: WO 92/20709 (1992-11-01), None
N. Chartrel et al., “Frog Vasoactive Intestinal Polypeptide and Galanin: Primary Structures and Effects on Pituitary Adenylate Cyclase”, Endocrinology, vol. 136, No. 7, PP.3079-3086(1995).
Å. Norberg et al., “Chemical detection of natural peptides by specific structures”, Federation of European Biochemical Societies, vol. 288, No. 1,2, PP. 151-153(1991).
K. Tatemoto et al., “Galanin—a novel biologically active peptide from porcine intestine”, Federation of European Biochemical Societies, vol. 164, No. 1, PP. 124-128(1983).
Å. Rökaeus et al., “Construction of a porcine adrenal medullary cDNA library and nucleotide sequence analysis of two clones encoding a galaninn precursor”, Proc. Natl. Acad. Sci. USA, vol. 83, PP. 6287-6291(1986).
R. Sillard et al., “Variant Forms of Galanin Isolated From Porcine Brain”, Peptides, vol. 13, PP. 1055-1060(1992).
K. Smith et al., “Expression Cloning of a Rat Hypothalamic Galanin Receptor Coupled to Phosphoinositide Turnover”, The Journal of Biological Chemistry, vol. 272, No. 39, PP. 24612-24616(1997).
S. Wang et al., “Cloning and Expressional Characterization of a Novel Galanin Receptor”, The Journal of Biological Chemistry, vol. 272, No. 51, PP.31949-31952(1997).
K. Smith et al., “Cloned Human and Rat Galanin GALR3 Receptors”, The Journal of Biological Chemistry, vol. 273, No. 36, PP. 23321-23326(1998).
Ishibashi Yoshihiro
Kitada Chieko
Matsui Hideki
Ogi Kazuhiro
Ohtaki Tetsuya
Chao Mark
Pak Michael
Ramesh Elaine M.
Takeda Pharmaceutical Company Limited
LandOfFree
Physiologically active peptide and its use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Physiologically active peptide and its use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Physiologically active peptide and its use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3678916