Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1988-10-27
1991-09-03
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Lymphokine
514 12, 514 21, 530363, 530391, A61K 3736, A61K 3944, A61K 39395
Patent
active
050453122
ABSTRACT:
Growth hormone is conjugated to any ligand, preferably a protein such as bovine serum albumin, optionally by use of a cross-linking agent such as a carbodiimide. The conjugates have enhanced activity when compared with unmodified growth hormone, and also better aqueous solubility at acid pH's.
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Aston Roger
Bomford Robert
Holder Andrew T.
Brown Donald
Burroughs Wellcome Co.
Koh Choon P.
Schain Howard E.
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