Physically stable composition and method of use thereof for osse

Details Physically stable composition and method of use thereof for osse Physically stable composition and method of use thereof for osse

1987-07-28

1988-10-25

Rosen, Sam

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 7, 623 16, A61K 3702, A61K 3712

Patent

active

047804505

ABSTRACT:
A composition for osseous repair which is prepared by a process comprising mixing a particulate polycrystalline calcium phosphate ceramic, a phosphophoryn calcium salt and type I collagen, preferably in a weight ratio of ceramic:calcium salt:collagen of about 775-15:3-0.1:1, to yield a solid porous composition which is effective to promote new bone formation upon introduction of the composition into osseous defects.

REFERENCES:
patent: 4563350 (1986-01-01), Nathan et al.
patent: 4619655 (1986-10-01), Hanker et al.
R. E. Grundel et al., 33rd Annual Meeting, Orthopaedic Res. Society, San Francisco, Calif. (Jan. 19-22, 1987).
M. Jarcho, Clinical Orthopaedic and Related Research, 157, 259 (1981).

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