Physical mapping method using molecular combing technique...

Details Physical mapping method using molecular combing technique... Physical mapping method using molecular combing technique...

2003-03-11

2008-05-06

Horlick, Kenneth R. (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

Reexamination Certificate

active

07368234

ABSTRACT:
A method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA where the method can include: (a) fixing and combing a certain amount of the B DNA on a combing surface; (b) reacting the product of step (a) with one or several probes, linked with the gene(s) or specific A DNA sequences, or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes, (2) the distance between the probes, (3) the size of the probes (the total sum of sizes for quantifying the number of hybridized probes) and determining from this extracted information the presence, the location and/or the amount of a gene(s) or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.

REFERENCES:
patent: 5079169 (1992-01-01), Chu et al.
patent: 5356776 (1994-10-01), Kambara et al.
patent: 5660988 (1997-08-01), Duck et al.
patent: 5677126 (1997-10-01), Bensimon et al.
patent: 5707797 (1998-01-01), Windle
patent: 5840862 (1998-11-01), Bensimon et al.
patent: 5846724 (1998-12-01), Bensimon et al.
patent: 5851769 (1998-12-01), Gray et al.
patent: 6054327 (2000-04-01), Bensimon et al.
patent: 6265153 (2001-07-01), Bensimon et al.
patent: 6294324 (2001-09-01), Bensimon et al.
patent: 6303296 (2001-10-01), Bensimon et al.
patent: 6548255 (2003-04-01), Bensimon et al.
patent: 2003/0175779 (2003-09-01), Bensimon et al.
patent: WO 93/18186 (1993-09-01), None
patent: WO 95/09929 (1995-04-01), None
patent: WO 95/21939 (1995-08-01), None
patent: WO 96/17958 (1996-06-01), None
patent: WO 97/18326 (1997-05-01), None
Parra et al., Nature Genetics 5, 17-21 (1993).
Lebofsky et al., Briefings in Functional Genomics and Proteomics 1(4), 385-396 (2003).
Lichter et al., “High-Resolution Mapping of Human Chromosomes 11 by In Situ Hybridization With Cosmid Clones”,Science, vol. 247, pp. 64-69 (1990).
du Manoir et al., “Detection of Complete and Partial Chromosome Gains and Losses by Comparative Genomic In Situ Hybridization”,Hum. Genet., vol. 90, pp. 590-610 (1993).
Kallioniemi et al., “Comparative Genomic Hybridization for Molecular Cytogenic Analysis of Solid Tumors,”Science, vol. 258, pp. 818-821 (Oct. 30, 1992).
International Search Report for PCT/FR97/01949 (and English version), Oct. 30, 1997.
Desmaze et al., “In Situ Hybridization of Fluorescent Probes on Chromosomes, Nuclei or Stretched DNA: Applications in Physical mapping and Characterization of Genomic Rearrangements”,Cellular and Molecular Biology, 41(7), pp. 925-931 (1995).
du Manoir et al., “Quantitative Analysis of Comparative Genomic Hybridization”,Cytometry, vol. 19, pp. 27-41 (1995).
Bensimom et al., “Alignment and Sensitive Detection of DNA by a Moving Interface”,Science, vol. 265, pp. 2096-2098 (Sep. 30, 1994).
Piper et al., “Computer Image Analysis of Comparative Genomic Hybridization”,Cytometry, vol. 19, pp. 10-26 (1995).
Michalet et al.,Science, vol. 277, pp. 1518-1523 (Sep. 1997).

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