Physalia fluorescent proteins

Details Physalia fluorescent proteins Physalia fluorescent proteins

2005-05-31

2005-05-31

Wax, Robert A. (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S004000, C435S069100, C435S320100, C435S325000

Reexamination Certificate

active

06900289

ABSTRACT:
Provided arePhysaliafluorescent proteins (PFPs) and, more particularly, to PFPs of aPhysaliaspecies, and methods of detecting and isolating PFPs. Also provided are methods and compositions for using PFPs, including recombinant PFPs, as reporter molecules in in vitro and in vivo biological assays, including screening assays and cellular assays.

REFERENCES:
patent: 4471470 (1984-09-01), Swainson et al.
patent: 5325324 (1994-06-01), Rentzepis et al.
patent: 5625048 (1997-04-01), Tsien et al.
patent: 6046925 (2000-04-01), Tsien et al.
patent: 6124128 (2000-09-01), Tsien et al.
patent: WO 96/23810 (1996-08-01), None
Irie, M. and Mori, M., “Thermally Irreversible Photochromic Systems. Reversible Photocyclization of Diarylethene Derivatives.” J. Org. Chem. 53:803-808 (1987).
Parthenopolous, D.A., and Rentzepis, P.M., “Three-Dimensional Optical Storage Memory.” Science. 245:843-845(1989).
Hanazawa, M., et al., “Thermally Irreversible Photochromic Systems. Reversible Photocyclization of 1,2-Bis-(2-methylbenzo[b]thiophen-3-yl)perfluorocycloalkene Derivatives.” J. Chem. Soc. Chem. Commun. 3:206-207(1992).
Dvornikov, A.S., et al., “Spectroscopy and Kinetics of Photochromic Materials for 3D Optical Memory Devices,” J. Phys. Chem. 98:6746-6752 (1994).
Dvornikov, A.S., and Rentzepis, P.M., “Process and Materials for Two-Photon Volume Optical Memories.” Opt. Mem. Neur. Netw. 3:75-86 (1994).
Ehrig, T., et al., “Green-fluorescent protein mutants with altered fluorescence excitation spectra.” FEBS Lett. 367:163-166 (1995).
Delagrave, S., et al., “Red-Shifted Excitation Mutants of the Green Fluorescent Protein.” Bio/Technology. 13:151-154 (1995).
Chattoraj, M., et al., “Ultra-fast excited state dynamics in green fluorescent protein: Multiple states and proton transfer .” Proc. Nat. Acad. Sci. USA 93: 8362-8367 (1996).
Brejc, K., et al., “Structural basis for dual excitation and photoisomerization of theAequorea victoriagreen fluorescent protein.” Proc. Nat. Acad. Sci. USA 94:2306-2311 (1997).
Ormo, M., et al., “Crystal Structure of theAequorea victoriaGreen Fluorescent Protein.” Science. 273:1392-1395 (1996).
Yang, F., et al, “The molecular structure of green fluorescent protein.” Nature Biotech. 14:1246-1251 (1996).
Ward, W.W., et al., “Spectral Perturbations of theAequoreaGreen-Fluorescent Protein.” Photochem. Photobiol. 35:803-808 (1982).
Levine, L.D., et al, “Isolation and Characterization of a Photoprotein, ‘Phialidin’, and a Spectrally Unique Green- Fluorescent Protein From The Bioluminescent JellyfishPhialidium gregarium.”Comp. Biochem. Physiol. 72B:77-85 (1982).
Prasher, D.C., et al., Primary structure of theAequorea victoriagreen-fluorescent protein. Gene. 111:229-233 (1992).
Tsien, R.Y., et al., “FRET for studying intracellular signalling.” Trends Cell Biol. 3:242-245 (1993).
Heim, R., and Tsien, R.Y., “Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer.” Current Biol. 6:178-182 (1996).
Cubitt, A.B., et al., “Understanding, improving and using green fluorescent proteins.” Trends in Biochem. Sci. 20:448-455 (1995).
Heim, et al., “Wavelength mutations and posttranslational autoxidation of green fluorescent protein.” Proc. Nat. Acad. Sci. USA. 91:12501-12504 (1994).
Alam, J. M. et al., “Isolation and physiopharmacological properties of three high molecular weight lethal proteins from a coelenterate (Physalia utriculus) venom,” Pakistan Journal of Zoology 28(3):245-252 (1996) (Abstract) Database: Biosis Biological Abstracts, Philadelphia; Acc. No. 1997:66562 Biosis, Doc. No. PREV199799365765.
Alam, J.M. et al., Biochemical characterization and pathophysiological properties of two high molecular weight cytolytic proteins from the venom of a coelenterate (Jellyfish),Physalia utriculus(Blue Bottle). Pakistan Journal of Zoology, 34(1):9-17 (2002) (Abstract) Database: Biosis Biological Abstracts, Philadelphia; Acc. No. 2002:500997, Doc. No. PREV200200500997.

Affiliated with

Also associated with

Rating

Physalia fluorescent proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Physalia fluorescent proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Physalia fluorescent proteins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3390463