Phthalyl amidase-producing Xanthobacter agilis

Details Phthalyl amidase-producing Xanthobacter agilis Phthalyl amidase-producing Xanthobacter agilis

1995-05-22

1996-07-02

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435228, 435822, 435910, C12N 780, C12N 112, C12N 120

Patent

active

055321615

ABSTRACT:
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides 2 phthalyl amidase, 2 method for producing it by culturing the natural organism from which the activity was identified, and methods for using the phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides. The ezyme is isolated from Xanthobacter agilis.

REFERENCES:
Yang et al., J. Biol. Chem. 268:10870, 1993.
Kukolja et al., Croatica Chemica Acta 49:779, 1977.
Toyoura et al., Chem. Pharm. Bull. 7:789, 1959.

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