Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-10-24
1981-11-24
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544139, 544144, 2603433R, C07D40504, A61K 3147
Patent
active
043024580
ABSTRACT:
The phthalidyl-isoquinoline derivatives have the formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.4, R.sub.5 and R.sub.6 each denotes a lower alkoxy group, R.sub.3 denotes a hydrogen atom or a lower alkoxy group and R.sub.7 denotes a lower alkyl group and also include their diastereoisomers and their addition salts with pharmaceutically acceptable acids.
These compounds have antiallergic activities and may be used to treat allergic symptoms in human beings and other animals.
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patent: 3277085 (1966-10-01), Aebi et al.
patent: 3796712 (1974-03-01), Leimgruber et al.
Merck Index, 1976, p. 1252, Abstract No. 9428.
Merck Index, 1976, p. 872, Abstract No. 6528.
Kosmicki, et al., "J. Pharmacol" (Paris), vol. 5(3), 1974, pp. 331-342.
Taylor, J. Chim. Soc., 1951, pp. 1150-1157.
Brossi, "Helv. Chem. Acta", vol. 47(7), 1964, pp. 2089-2097.
Schenker, et al., "Helvetica Chimica Acta", vol. 47, No. 232, 1964, pp. 2089-2097.
Chazerain Jacques A.
Cotereau Hubert Y.
Lallouette Pierre H.
Legger Hugues A.
Lepape Pierre A. C.
Calaire Chimie, S.A.
Daus Donald G.
Laborec Laboratoire de Recherches Biologiques
Turnipseed James H.
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