Phototherapeutic monovinyl and divinyl ether-linked dimers

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 12, 514410, 530387, 530388, 530389, 530391, 540145, A61K 4900, A61K 3140, A61K 3704, C07D25900

Patent

active

049619209

ABSTRACT:
Pure dimer compounds prepared and shown to be effective photosensitizing agents are of the formula ##STR1## wherein one R is vinyl and the other R is hydroxyethyl or vinyl and the pharmaceutically acceptable esters and salts thereof in isolated form.

REFERENCES:
patent: 4500507 (1985-02-01), Wong
patent: 4512762 (1985-04-01), Spears
patent: 4634557 (1987-01-01), Sato et al.
patent: 4649151 (1987-03-01), Dougherty et al.
patent: 4727027 (1988-02-01), Wiesehahn et al.
patent: 4748120 (1988-05-01), Wiesehahn
patent: 4753958 (1988-06-01), Weinstein
Diamond et al., Lancet (1972) 2:1175-1177.
Dougherty et al., Cancer Res. (1978) 38:2628-2635.
Dougherty et al., "Porphyrin Localization and Treatment of Tumors" (1984), Alan R. Liss, Inc., pp. 301-314.
Dougherty et al., CRC Critical Rev. in Oncology/Hematology (1984) 2:83-116.
Gregorie et al., Ann. Surg. (1968) 167:820-828.
Mew et al., J. Immunol. (1983) 130:1473-1477.
Mew et al., Cancer Res. (1985) 45:4380-4386.
Weishaupt et al., Cancer Res. (1976) 36:2326-2329.
Morgan et al., Chem. Abstracts (1985) 102:61981s.
Richter et al., JNIC (1987) 79(6):1327-1331.
Pangka et al., Chem. Abstracts (1986) 104:207015v.
Dougherty et al., Adv. Exp. Med. Biol. (1983) 160:3-13.
Kessell et al., Photochem. Photobiol. (1987) 46(5):563-568.
Scourides et al., Cancer Res. (1987) 47:3439-3445.
Pandey et al., Cancer Res.
Morris et al., Tetrahedron Letters (1988) 29:2501-2504.
Lipson et al., J. Natl. Cancer Inst. (1961) 26:1-8.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Phototherapeutic monovinyl and divinyl ether-linked dimers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phototherapeutic monovinyl and divinyl ether-linked dimers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phototherapeutic monovinyl and divinyl ether-linked dimers will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-972311

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.