Photosensitizers for photodynamic therapy at infrared...

Details Photosensitizers for photodynamic therapy at infrared... Photosensitizers for photodynamic therapy at infrared...

2007-05-18

2010-10-12

Chin, Christopher L (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S525000, C436S527000, C436S172000

Reexamination Certificate

active

07811830

ABSTRACT:
A photosensitizer that is excitable via infrared radiation and is adapted to be used to treat a selected biological target. The photosensitizer comprises a core nanoparticle adapted to convert infrared radiation into a visible light emission, and a coating disposed about the core nanoparticle. The coating contains a light excitable agent that is adapted to be excited by the visible light emission from the core nanoparticle. The photosensitizer can be surface modified with an antibody to make the photosensitizer specific to the biological target that is to be treated. Such surface modified photosensitizer is introduced to the target site and irradiated with infrared radiation.

REFERENCES:
patent: 6548264 (2003-04-01), Tan et al.
patent: 2003/0124564 (2003-07-01), Trau et al.
patent: 2006/0223197 (2006-10-01), Vielsack
patent: 2007/0254981 (2007-11-01), DiMaio et al.

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