Photosensitizer and method for production thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C534S015000, C514S185000, C514S410000, C514S009100

Reexamination Certificate

active

06969765

ABSTRACT:
The invention relates to medicine and concerns a photosensitizer for detecting and curing tumors. The inventive photosensitizer is embodied in the form of a composition containing chlorin in the form of salt and alkali metals. The chlorin is composed of 80-90% of chlorin e6, 5-20 of purpurin 5 and the rest being purpurin 18 -chlorin p6. Said photosensitizer is produced by extracting Spirulina biomass with the aid of acetone. Afterwards said biomass is exposed to acid treatment, neutralization, hydrolysis, extraction of pheophorbidea, dissolution in acetone, addition of a strong base, neutralization and reprecipitation of chlorin e6.

REFERENCES:
patent: 5216012 (1993-06-01), Morgan et al.
patent: 5330741 (1994-07-01), Smith et al.
patent: 2054476 (1994-07-01), None
patent: 2152790 (2002-07-01), None

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