Photoreactive benzoylphenylalanines and related peptides

Details Photoreactive benzoylphenylalanines and related peptides Photoreactive benzoylphenylalanines and related peptides

1987-01-09

1988-08-09

Phillips, Delbert R.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

562441, 530334, C08F28300, C07C10142, C07K 104

Patent

active

047628812

ABSTRACT:
Provided is a benzoylphenylalanine of the formula: ##STR1## wherein ##STR2## is in the m or p position; and Pr is a protecting group which is easily cleavable in the presence of a peptide bond by a mild acid or base.
This benzoylphenylalanine group is incorporated into a peptide chain which can be attached to a solid substrate having a reactive hydrogen by exposure to low energy ultraviolet light.

REFERENCES:
Journal of Medicinal Chem. 16, No. 1 (1973) 60-64.
The Journal of Biol. Chem. 261 (1986) 10695-10700.
Chem. Abstr. vol. 53 (1959) 22509.
Chem. Abstr. vol. 53 (1959) 10559.
J. M. Robert Parker and Robert S. Hodges, J. Protein Chemistry 3, 465 (1985).
J. M. Robert Parker and Robert S. Hodges, J. Protein Chemistry 3, 479 (1985).

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