Photoproteins with enhanced bioluminescence and assays using...

Details Photoproteins with enhanced bioluminescence and assays using... Photoproteins with enhanced bioluminescence and assays using...

2011-07-19

2011-07-19

Prouty, Rebecca (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C530S350000, C536S023500, C435S320100, C435S252300, C435S325000

Reexamination Certificate

active

07981602

ABSTRACT:
The present invention relates to photoproteins with enhanced bioluminescence obtained by mutagenesis of clytin, to their use as intracellular calcium indicators and in cell-based assays.

REFERENCES:
patent: 5360728 (1994-11-01), Prasher
patent: 2005/0130262 (2005-06-01), Lambolez et al.
patent: 03/006497 (2003-01-01), None
K. Tsuzuki et al. “Thermostable Mutants of the Photoprotein Aequorin Obtained by in Vitro Evolution”, J. Biol. Chem. 280(40: 34324-34331. (Jun. 2005).

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