Photoprotection compositions comprising sorbohydroxamic acid

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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252106, 252107, 252108, 424DIG5, 424 59, 424 60, 424 63, 424 64, 424 70, 514844, 514846, 514847, 514873, 514937, 514938, 514939, 514944, 514945, 514969, 514972, A61K 706, A61K 742, A61K 748, A61K 912

Patent

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048698970

ABSTRACT:
Disclosed are pharmaceutical compositions comprising sorbohydroxamic acid, or pharmaceutically-acceptable salts thereof, which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of sorbohydroxamic acid together with tocopherol sorbate and/or sunscreens are also disclosed.
Also disclosed is a method for using these compositions topically, prior to UV exposure, to prevent damage to skin caused by acute or chronic UV exposure.

REFERENCES:
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patent: 4144325 (1974-03-01), Voyt
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patent: 4338293 (1982-07-01), Holick
patent: 4603146 (1986-07-01), Kligman
Ramos Arrocha, et al., Rev. Cubana Farm., 18 (1), 27-34, (1984).
Law, et al., Br. J. Pharm., 59(4), 591-594 (1977).
Kaidbey, J. Invest. Derm., 66, 153-156 (1976).
Gruber, et al., Clinical Pharm. and Therapeut., 13(1), 109-113 (1971).
Liu, Chemical Abstracts, 1977, vol. 86, p. 678325.

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