Photon reducing agents for fluorescence assays

Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence

Reexamination Certificate

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C436S501000, C436S528000, C436S529000, C436S530000, C436S531000, C436S546000, C436S800000, C436S809000, C436S063000, C435S005000, C435S006120, C435S007100, C435S007200, C435S007500, C435S007210, C435S029000, C435S040500, C435S230000, C435S235100, C435S288300, C435S288400, C427S102000, C427S157000, C427S213340, C422S082050, C422S091000

Reexamination Certificate

active

07067324

ABSTRACT:
The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides a method for reducing undesirable light emission from a sample (e.g., a biochemical or cellular sample) with at least one photon producing agent and at least one collisional quencher. The present invention also provides a method for reducing undesirable light emission from a sample (e.g., a biochemical or cellular sample) with at least one photon producing agent and at least one quencher, such as an electronic quencher. The present invention also provides a system and method of screening test chemicals in fluorescent assays using photon reducing agents. The present invention also provides compositions, pharmaceutical compositions, and kits for practicing these methods.

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