Photoelectric synthesis of DNA or protein probe arrays

Electrolysis: processes – compositions used therein – and methods – Electrolytic coating – Utilizing electromagnetic wave energy during coating

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205 92, 205118, 205122, 205317, 205340, 205414, 205419, 205424, C25D 500, C25D 502, C25B 300

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active

058109897

ABSTRACT:
A method of photoelectro-synthesizing probe arrays including the steps of providing a photoconductive layer of material having a layer of electrically conductive material on a first surface thereof and a solution of a plurality of a first oligonucleotide modified monomer positioned in electrical contact with an opposing second surface thereof such that a potential is connected therebetween. A beam of light is directed through a portion of the photoconductive layer of material to complete an electrical circuit between the layer of electrically conductive material and the solution through the portion of the photoconductive layer, whereby the monomers in the solution are electropolymerized on a surface area which is coupled into the electrical circuit by the beam of light.

REFERENCES:
Roget et al., "Electrochemically Directed Copolmerization of Pyrrole and Oligonucleotides", Nucleosides & Nucleotides, 14(3-5), pp. 943-946, 1995.

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