Photodynamic therapy utilizing a solution of...

Surgery – Instruments – Orthopedic instrumentation

Reexamination Certificate

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Reexamination Certificate

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09514070

ABSTRACT:
The invention relates to a method of photoeradication of cells at a tissue site, such as an infection or sterilization site or cancer cell activity site, including applying a solution such as methylene blue, toluidene blue, polymyxin B, SDS, or other surfactants and combinations thereof to the tissue site and exposing the tissue site with a light having a light wavelength and light dosage and a light dosage rate. The solution may have a concentration of methylene blue between 5 μg/ml to about 100 μg/ml. The wavelength may range from about 610 nm to about 670 nm. The light dosage may range from about 0 J/cm2to about 200 J/cm2. The light dosage rate may range from about 0 mw/cm2to about 150 mw/cm2. Treatable organisms includecandida albicans, escherechia coli, pseudomonas aeruginosa, staphylococcus aureus, streptococcus pneumoniae, andclostridia.

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