Photodynamic activity of sapphyrins

Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

20415761, C07D48722, C07F 500

Patent

active

051204118

ABSTRACT:
The present invention includes a method to produce singlet oxygen from molecular oxygen generated by reaction with a sapphyrin compound excited at an absorbing wavelength to form a triplet species. Specifically, the sapphyrin compound is an alkylated sapphyrin, most preferably diprotonated 3,8,12,13,17,22-hexaethyl-2,7,18,23-tetramethylsapphyrin. Generation of the triplet species may be accomplished in an organic solvent, of which the most preferable solvents are chloroform, methanol or acetonitrile.
Also encompassed within the present invention is a method to selectively produce singlet oxygen in an aqueous environment. A sapphyrin compound is incorporated within a membranous vesicle, the vesicle is illuminated with exciting light and the resultant excited triplet state sapphyrin compound reacts with molecular oxygen to produce singlet oxygen. Singlet oxygen was not generated external to the vesicle where the sapphyrin compound is present in an aqueous medium.

REFERENCES:
patent: 4883790 (1989-11-01), Levy et al.
patent: 4915683 (1990-05-01), Sieber
patent: 4935498 (1990-06-01), Sessler et al.
PCT Search Report, mailed 2 Aug. 1990.
Harriman et al., J. Chem. Soc., Chem. Commun., (1989) 314-316.
Sessler et al., Chem. Absts., vol. 111:125716e (2 Oct. 1989).
Sessler et al., J. Amer. Chem. Soc., 110(16):5586-5588 (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Photodynamic activity of sapphyrins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Photodynamic activity of sapphyrins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Photodynamic activity of sapphyrins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1802367

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.