Photocurable glycosaminoglycan derivatives, crosslinked glycosam

Details Photocurable glycosaminoglycan derivatives, crosslinked glycosam Photocurable glycosaminoglycan derivatives, crosslinked glycosam

1993-02-05

1995-10-31

Berman, Susan W.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Compositions to be polymerized by wave energy wherein said...

522 78, 522 79, 522 84, 522 86, 522 87, 522 88, 523105, 523111, 527312, 527313, 527314, 527315, C08L 508, C08L 500, C08J 328

Patent

active

054629764

ABSTRACT:
Photocurable glycosaminoglycan (GAG) derivatives and crosslinked glycosaminoglycans, which are highly safe and biocompatible, a method of preparing such photocurable GAG derivatives readily moldable by casting using a solvent when desired, by which method unreacted substances causative of adverse effects can be readily eliminated, and a method of producing the crosslinked GAGs and medical materials based on the photocurable GAG derivatives or crosslinked GAGs are provided. The photocurable GAG derivatives comprise a glycosaminoglycan and a photoreactive compound bound thereto and can be produced, for example, by subjecting hydroxyl or carboxyl groups of the glycosaminoglycan to esterification reaction or amidation reaction, respectively, with the photoreactive compound. The crosslinked GAGs are derived from the photocurable GAG derivatives by intermolecular crosslinking of the photoreactive compound bound thereto.

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