Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy
Patent
1992-05-18
1996-08-06
Niebling, John
Chemistry: electrical and wave energy
Processes and products
Processes of treating materials by wave energy
20415715, 20415767, C07B 6100
Patent
active
055430163
ABSTRACT:
The photoconversion of steroids is carried out in microreactors to yield desired products, while limiting the formation of undesirable byproducts. The steroid reactant is combined with a microreactor such as solid particles having controlled spaces of appropriate size to provide stereochemical control over the reaction. Appropriate catalyst particles include silica and zeolitic material. The reaction can be conducted in a fluidized bed reactor and the formation of undesirable byproducts can be effectively limited.
REFERENCES:
patent: 3838029 (1974-09-01), Fischer
patent: 3929770 (1975-12-01), Ishikawa et al.
patent: 4265822 (1981-05-01), Deluca et al.
patent: 4388242 (1983-06-01), Malatesta et al.
patent: 4551214 (1985-11-01), Hansen et al.
patent: 4609444 (1986-09-01), Guillet
patent: 4686023 (1987-08-01), Stevens
patent: 4937292 (1990-06-01), Slemon
patent: 5035783 (1991-07-01), Goethals et al.
patent: 5252191 (1993-10-01), Pauli et al.
Facaha et al., "Surface Photochem . . . ".
F. Boomsma, et al., The "Overirradiation products" of Previtamin D and Tachysterol: Toxisterols.sup.1-3 ; Journal of the Royal Netherlands Chemical Society, Apr. 1977, vol. 96(4), pp. 104-112.
O. A. de Bruin, et al., Retro-steriod -A New Class of Compounds with Sex-hormone Action, Philips Technical Review , vol. 28, pp. 70-79.
William S. Allen, et al., Steroidal Cyclic Ketals. XI. The Conversion of 11-epi-Hydrocortisone into Hydrocortisone, vol. 76, Dec. 5, 1954, pp. 6116-6119.
M. P. Rappoldt, et al., Investigations on Sterols XXXVII -New Routes to 9,10-isomers of 6-dehydroprogesteron, Recueil, vol. 90 (1971), pp. 27-32.
R. Antonucci, et al., .DELTA..sup.5,7 -Steroids, XIII, Steroidal Cyclic Ketals. II.sup.1,2 The Preparation of .DELTA..sup.4,7 -Pregnadiene-3, 20-Dione and .DELTA..sub.4,7 -Pregnadiene-2l-OL-3,20-Dione-Acetate, Journal of Organic Chemistry, vol. 17, pp. 1369-1374 (1952).
R. M. Moriarty, et al., Formation of Vitamin D.sub.3 in Synthetic Lipid Multibilayers. A Model for Epidermal Photosynthesis, Journal of the American Chemical Society, Jun., 1980, vol. 102:12, pp. 4257-4259, Jun. 1980.
V. Malatesta, et al., Laser Photochemical Production of Vitamin D.sup.1, Journal of the American Chemical Society, vol. 103, pp. 6781-6783 (1981).
W. G. Dauben, Wavelength-Controlled Production of Previtamin D.sub.3, Journal of the American Chemical Society, vol. 104, pp. 355-356 (1982).
Rajeev Farwaha, et al., Surface Photochemistry: Enone Photocycloaddition by Absorbed Molecules on Silica Gel and Alumina.sup.1, Journal of Organic Chemistry, vol. 50, No. 2, 245-250 (1985).
D. H. R. Barton, A Convenient Synthesis of 1.alpha.-Hydroxy-Vitamin D.sub.3, Journal of the American Chemical Society, vol. 95:8, pp. 2748-2749 (Apr. 1973).
M. Fischer, Industrial Applications of Photochemical Synthesis, Angew. Chem. Int. Ed. Engl., vol. 17, pp. 16-26 (1978).
K. Takada, et al., Isolation and Identification of Tachysterol.sub.3 in Rat Skin Exposed to Ultraviolet Light, Biochimica et. Biophysica Acta, 666 (1981), pp. 356-360.
Chemical Abstracts Service, Search on Vitamin D.sub.3 1.alpha.-Hydroxy Vitamin D.sub.3 Photochemical Synthesis -31 references.
Fehlner James R.
Firnberg Dow
Delacroix-Muirheid C.
Inrad
Niebling John
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