Photocleavable protecting groups and methods for their use

Details Photocleavable protecting groups and methods for their use Photocleavable protecting groups and methods for their use

1997-03-05

2000-11-14

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 221, 536 231, 536 253, 536 2532, 536 2533, 536 2534, 536 2626, 536 266, 536 2671, 536 2672, 536 2673, 536 2674, 536 2713, 536 276, 536 278, 536 2781, 536 284, 536 285, 536 2853, 536 2854, C07H 2100, C07H 1900

Patent

active

061472050

ABSTRACT:
Novel compounds are provided which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Ar--C(R.sub.1)(R.sub.2)--O--C(O)-- wherein:

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