Photochemically crosslinked collagen scaffolds and methods...

Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy

Reexamination Certificate

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C204S157680, C424S422000, C424S456000, C424S484000, C530S356000

Reexamination Certificate

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07393437

ABSTRACT:
A method for producing collagen-based scaffolds with improved characteristics, which broadens the usage of collagen in tissue engineering and the products so produced are described. The method comprises reconstitution of three-dimensional collagen matrices from collagen monomer solution and crosslinking the matrix with a light source in the presence of a photosensitizing reagent. The crosslinked products can be in any shape and form and used in the dry or wet state, for applications including but not limited to tissue engineering and controlled drug delivery.

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