Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2011-08-30
2011-08-30
Schnizer, Richard (Department: 1635)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S460000, C435S173500, C514S04400A
Reexamination Certificate
active
08008077
ABSTRACT:
The present invention provides a method for introducing a molecule into the cytosol of a cell in which the cell is contacted with a photosensitising agent, the cell is irradiated with light of a wavelength effective to activate the photosensitising agent and, substantially at the same time or after the irradiation, the cell is contacted with the molecule to be introduced, particularly for use in cancer treatment, gene therapy and vaccination.
REFERENCES:
patent: 5264618 (1993-11-01), Felgner et al.
patent: 5876989 (1999-03-01), Berg et al.
patent: 6153639 (2000-11-01), Sternberg et al.
patent: 6680301 (2004-01-01), Berg et al.
patent: 7223600 (2007-05-01), Berg et al.
patent: 2209468 (1989-05-01), None
patent: 176786 (1985-05-01), None
patent: 173319 (1986-04-01), None
patent: 891491 (1989-11-01), None
patent: 176947 (1990-05-01), None
patent: 176645 (1990-06-01), None
patent: 900731 (1990-06-01), None
patent: 300499 (1992-10-01), None
patent: 301981 (1993-12-01), None
patent: 180742 (1994-04-01), None
patent: 9314142 (1993-07-01), None
patent: 9507077 (1995-03-01), None
patent: 9607432 (1996-03-01), None
patent: 9628412 (1996-09-01), None
patent: 9830242 (1998-07-01), None
patent: 0053722 (2000-09-01), None
patent: 0054802 (2000-09-01), None
patent: 0209690 (2002-02-01), None
Miller et al. (FASEB J. 9: 190-199, 1995).
Deonarain (Exp. Opin. Ther. Patents 8(1):53-69, 1998).
Verma et al (Nature 389: 239-242, 1997).
Crystal (Science 270: 404-410, 1995).
Read et al (Adv. Gen. 53:19-46, 2005).
Korbelik et al (Cancer Res. 59: 1941-1946, 1999).
Ma et al (Rad. Res. 134: 22-28, 1993).
Fujiwara et al (Cancer Res. 42: 1487-1491, 1982).
Noguchi et al (Bioconjugate Chem. 3:132-137, 1992.
Moan et al (Proc. SPIE 2625:187-193, 1996).
Forssen et al (Proc. Am. Assoc. Cancer Res. Annual meeting) 34(0), 365, 1993).
Pass (J. Nat. Canc. Inst. 85(6): 443-456, 1993).
Governatore et al (Br. J. Canc. 82(1): 56-64, 2000).
Andreansky et al (Gene Therapy 5: 121-130, 1998).
Anderson (Nature 392:25-30, 1998).
Romano et al (Stem Cells 18: 19-39, 2000).
Somia and Verma (Nature Reviews Genetics 1: 91-99, 2000).
Rosenberg et al (Science 287 :1751, 2000).
Yokota et al (Int. J. Cancer 44(6): 1095-9, 1989).
Fretz et al (Biochim. Biophys. Acta 1665: 48-56, 2004).
Proffitt et al (J. Nucl. Med. 24: 45-51, 1983).
Kitamura (Cancer Res. 51: 4310-4315, 1991).
Prasmickaite, L. et al. “Role of endosomes in gene transfection mediated by photochemical internalisation (PCI),” The Journal of Gene Medicine (2000) 2(6): 477-488.
Rosenkranz, A. A. et al. “Targeted intracellular delivery of photosensitizers to enhance photodynamic efficiency,” Immunology and Cell Biology (2000) 78(4): 452-464.
Berg, K. et al. “Lysosomes and Microtubes as Targets for Photochemotherapy of Cancer,” Photochemistry and Photobiology (1997) 65: 403-409.
Berg, K. et al. “Verapamil enhances the uptake and the photocytotoxic effect of PII, but not that of terra (4-sulfonatophenyl) porphine,” Biochimica et Biophysica Acta (1998) 1370: 317-324.
Berg, K. et al. “Photochemical Internalization: A Novel Technology for Delivery of Macromolecules into Cytosol,” Cancer Research (1999) 59: 1180-1183.
Berg, K. et al. “Lysosomes as Photochemical Targets,” Int. J. Cancer (1994) 59: 814-822.
Berg, K. et al. “Photochemical Internalisation: A novel technology for improving macromolecule-based therapy,” Photodynamic News (2001) 4: 2-5.
Canti, G. et al. “Antitumor immunity induced induced by photodynamic therapy with aluminum disulfonated phthalocyanines and laser light,” Anti-Cancer Drugs (1994) 5: 443-447.
De Vree, W. J. A. et al. “Evidence for an Important Role of Neutrophilis in the Efficacy of Photodynamic Therapy in Vivo,” Cancer Research (1996) 56: 2908-2911.
Dougherty, T. G. et al. “Photodynamic Therapy,” Journal of the National Cancer Institute (1998) 90(12): 889-905.
Folini, M. et al. “Photochemical Internalization of a Peptide Nucleic Acid Targeting the Catalytic Subunit of Human Telomerase,” Cancer Research (2003) 63: 3490-3494.
Hogset, A. et al. “Photochemical Transfection: A New Technology for Light-Induced, Site-Directed Gene Delivery,” Human Gene Therapy (2000) 11: 869-880.
Korbelik, M. et al. “Photodynamic Therapy-mediated Immune Response against Subcutaneous Mouse Tumors,” Cancer Research (1999) 59: 1941-1946.
Lapes, M. et al. “Photodynamic therapy of cutaneous metastases of breast cancer after local application of meso-tetra-(para-sulphophenyI)-Porphin,” Journal of Photochemistry and Photobiology B (1996) 36: 205-207.
Lynch, D. H. “Systemic Immunosuppresion induced by Photodynamic Therapy (PDT) is Adoptively Transferred by Macrophages,” Photochemistry and Photobiology (1989) 49: 453-458.
Moan, J. et al. “The Photodegradation of Porphyrins in Cells can to used to Estimate the Lifetime of Singlet Oxygen,” Photochemistry and Photobiology (1991) 53: 549-553.
Moan, J. et al. “Sulfonated aluminium Phthalocyanines as Sensitizers for Photochemotheapy Effects of Small Light Doses of Localization, Dye Fluorescence and Photosensitivity in V79 Cells,” Int. J. Cancer (1994) 58: 865-870.
Normand, N. et al. “Particle Formation by a Conserved Domain of the Herpe Simplex Virus Protein VP22 Facilitating Protein and Nucleic Acid Delivery,” The Journal of Biological Chemistry (2001) 276: 15042-15050.
Prasmickaite, L. et al. “Evaluation of Different Photosensitizers for Use in Photochemical Gene Transfection,” Photochemistry and Photobiology (2001) 73(4): 388-395.
Selbo, P. K. et al. “Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization,” Biochimica et Biophysica Acta (2000) 1475: 307-313.
Selbo, P. K. et al. “Photochemical Internalisation Increase the Cytotoxic Effect if the Immunotoxin MOC31-Gelonin,” Int. J. Cancer (2000) 87: 853-859.
Selbo, P. K. et al. “5-Aminolevulinic Acid-Based Photochemical Internalization of the Immunotoxin MOC31-gelonin Generates Synergistic Cytotoxic Effects in Vitro,” Photochemistry and Photobiology (2001) 74(2): 303-310.
Selbo, P. K. et al. “In Vivo Documentation of Photochemical Internalization, a Novel Approach to Site Specific Cancer Therapy,” Int. J. Cancer (2001) 92: 761-766.
Thilo, L. et al. “Maturation of early endosomes and vesicular traffic to lysosomes in relation to membrane recycling,” Journal of Cell Science (1995) 108: 1791-1803.
Verma et al (Nature 389: 239-242, 1997).
Anderson (Nature 392: 25-30, 1998).
Romano et al (Stem Cells 18: 19-39, 2000).
Somia and Verma (Nature Reviews Genetics 1: 91-99, 2000).
Ma et al (Rad. Res. 134: 22-28, 1993).
Fujiwara et al (Cancer Res. 42: 1487-1491, 1982).
Noguchi et al (Bioconjugate Chem. 3: 132-137, 1992).
Moan et al (Proc. SPIE 2625: 187-193, 1996).
Forssen et al (Proc. Am. Assoc. Cancer Res. Annual meeting) 34(0), 365, 1993.
Dermer (Biotechnology 12: 320, 1994).
Berg Kristian
Hogset Anders
Prasmickaite Lina
Selbo Pal Kristian
Cantor & Colburn LLP
PCI Biotech AS
Schnizer Richard
LandOfFree
Photochemical internalization for delivery of molecules into... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Photochemical internalization for delivery of molecules into..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Photochemical internalization for delivery of molecules into... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2652777