Photoanalysis apparatus with means for correcting flow rate of f

Details Photoanalysis apparatus with means for correcting flow rate of f Photoanalysis apparatus with means for correcting flow rate of f

1988-06-07

1989-09-05

McGraw, Vincent P.

Optics: measuring and testing

Blood analysis

2504612, 356 72, G01N 3348, G01N 2164

Patent

active

048632643

ABSTRACT:
A photoanalysis apparatus includes marker pouring device for pouring markers into one of sheath fluid and fluid carrying particles in a flow-cell device, second optical device for applying a light beam for correction to the markers in the flow-cell device to measure strength of fluorescence or light scattering caused by said markers to generate a signal for correction, second signal processing device for calculating from the signal for correction at least one of a difference in position between a center of the fluid carrying particles in the flow-cell device and a center of a light beam for examination and a difference in flow rate between a predetermined flow rate and an actual flow rate of the fluid carrying particles in the flow-cell device to generate correspondingly at least one of a first command signal for position correction and a second command signal for flow rate correction, and correspondingly at least one of first correcting device for shifting the center of the light beam for examination to the center of the flow of the fluid carrying particles in accordance with the first command signal and second correcting device for correcting the flow rate of the fluid carrying particles to the predetermined flow rate in accordance with the second command signal.

REFERENCES:
patent: 3873204 (1975-03-01), Friedman et al.
patent: 4643566 (1987-02-01), Ohe et al.
Kamentsky et al, "Spectrophotometer: New Instrument for Ultrarapid Cell Analysis", Science, vol. 150, pp. 630-631, Oct. 1965.
Eisert, "Sample Flow Microphotometer for Rapid Cell Population Analysis", Rev. Sci. Instrum., vol. 46, No. 5, pp. 1021-1024, Aug. 1975.

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