Photoactivated collision induced dissociation (PACID)...

Details Photoactivated collision induced dissociation (PACID)... Photoactivated collision induced dissociation (PACID)...

2006-08-18

2010-10-19

Nguyen, Kiet T (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

Reexamination Certificate

active

07816644

ABSTRACT:
The invention provides a system apparatus and methods for fragmenting various molecules. In particular, the invention may be employed for fragmenting biomolecules like peptides to determine sequence information. The invention provides a mass spectrometry system for photo-activated collision induced dissociation. The mass spectrometry system or device includes an ion source for producing ions, a photon source adjacent to the ion source for photo-activating ions produced by the ion source, an electrical element adjacent to the photon source for creating an electric field for accelerating ions produced by the ion source and photo-activated by the photon source; wherein ions are produced by the ion source, photo-activated by the photon source and accelerated into a surface to cause dissociation of the activated ions; and a detector downstream from the ion source for detecting the collision induced and dissociated ions.

REFERENCES:
patent: 5073713 (1991-12-01), Smith et al.
patent: 6828549 (2004-12-01), Schweikhard et al.
patent: 7429728 (2008-09-01), Enke

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