Combinatorial chemistry technology: method – library – apparatus – Tag or label specially adapted for combinatorial chemistry...
Reexamination Certificate
2003-12-23
2010-06-15
Low, Christopher (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Tag or label specially adapted for combinatorial chemistry...
C536S025320, C435S068100, 53
Reexamination Certificate
active
07737089
ABSTRACT:
The present invention relates to a process for synthesizing biopolymers by stepwise assembly from protected synthesis building blocks which carry two-stage protective groups. The two-stage protective groups are activated by a first illumination step and eliminated by a subsequent chemical treatment step. Photoactivatable components which considerably speed up the activation process via intramolecular triplet sensitizers or/and have fluorescence properties are used. The two-stage protective groups can be used in particular within the framework of quality control.
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Happ et al., “New Trityl-Based Protecting Groups with a Mild Two-Step Removal”,Nucleosides&Nucleotides, vol. 7, No. 5/6, 1988 pp. 813-816.
Beijer Barbro
Güimil Ramon
Scheffler Matthias
Febit Holding GmbH
Gross Christopher M
Low Christopher
Rothwell Figg Ernst & Manbeck P.C.
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