Phosphorylcholine group containing compound and surface...

Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing

Reexamination Certificate

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Reexamination Certificate

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07906670

ABSTRACT:
A phosphorylcholine group-containing chemical compound represented by the following formula (1).In this formula, m denotes 2-6 and n denotes 1-4.X1, X2, and X3, independent of each other, denote a methoxy group, ethoxy group, or halogen. Up to two of X1, X2, and X3can be any of the following groups: a methyl group, ethyl group, propyl group, isopropyl group, butyl group, or isobutyl group.R is one of the structures in the following formulas (2)-(4) (the chemical compound of formula (1) in the structures of the following formulas (2)-(4) is expressed as A-R—B).In formulas (2)-(4), L is 1-6, P is 1-3.Also a surface modifier consisting of the aforementioned phosphorylcholine group-containing chemical compound, modified powder treated with said surface modifier, a chromatography packing consisting of a modified carrier treated with said surface modifier, a filter treated with said surface modifier, and a glass device treated with said surface modifier.

REFERENCES:
patent: 1750158 (2007-02-01), None
patent: 2005112871 (2005-12-01), None
Lu et al., {Reduced Protein Adsorption on the Surface of a Chemically Grafted Phospholipid Monolayer, Langmuir, 2001, 17(11), 3382-3389}.
Lu, Jian R., et a. “ Reduced Protein Adsorption On The Surface Of A Chemically Grafted Phospholipid Monolayer”, Langmuir, 17(11), 3382-3389.
Supplementary European Search Report issued in counterpart European Application No. EP 04 81 9845.

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