Phosphorylated materials as contrast agents for use in magnetic

Details Phosphorylated materials as contrast agents for use in magnetic Phosphorylated materials as contrast agents for use in magnetic

1995-12-22

1999-03-23

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424 9363, 514836, 436173, A61B 5055

Patent

active

058855491

ABSTRACT:
Methods of providing an image of the gastrointestinal region of a patient and diagnosing the presence of any tumorous tissue in that region using contrast media comprising a combination of at least one polyphosphorylated aliphatic or polyphosphorylated alicyclic compound and at least one paramagnetic ion, wherein the aliphatic and alicyclic compounds comprise at least five carbon atoms, is described. Also described are diagnostic kits for gastrointestinal imaging which include the subject contrast media.

REFERENCES:
patent: 4532217 (1985-07-01), Springer, Jr. et al.
patent: 4615879 (1986-10-01), Runge et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4719098 (1988-01-01), Weinmann et al.
patent: 4749560 (1988-06-01), Elgavish
patent: 4804529 (1989-02-01), Bardy et al.
patent: 4867963 (1989-09-01), Maurer et al.
patent: 4880007 (1989-11-01), Sadler et al.
patent: 4909257 (1990-03-01), Engelstad et al.
patent: 4915933 (1990-04-01), Matwiyoff
patent: 4972837 (1990-11-01), Engelstad et al.
patent: 4986980 (1991-01-01), Jacobsen
patent: 5236695 (1993-08-01), Winchell et al.
Conti et al., Gadolinium Complexes as Contrast Agents for Liver NMR Imaging*, Inorganica Chimica Acta, vol. 140, pp. 355-357 (1987).
Bales et al., in "Nutritional Availability of Manganese", Kies, Ed., American Chemical Society, Washington, D.C., 1987, Ch. 11, pp. 112-122.
Bothwell et al., J. of Internal Medicine 1989, 226, 357-365.
Bothwell et al., "Iron Metabolism in Man", Blackwell Scientific Publications, Oxford, England, 1979, Ch. 12.
Breitenbach et al., in "Phytic Acid: Chemistry and Applications", Graf, Ed., Pilatus Press, Minneapolis, MN, 1986, pp. 127-130.
Davies et al., British J. of Nutrition 1975, 34, 243-258.
Gruden, in "Nutritional Bioavailability of Manganese", Kies, Ed., American Chemical Society, Washington, DC, 1987, Ch. 7, pp. 67-79.
Hallberg et al., American J. of Clinical Nutrition 1989, 49, 140-144.
Hallberg et al., American J. of Clinical Nutrition 1987, 45, 988-996.
Hurley in "Clinical, Biochemical and Nutritional Aspects of Trace Elements", Prasad, Ed., Alan R. Liss, Inc., 1982, Ch. 20, pp. 369-378.
Kean, D.M. and M.A. Smith, "Magnetic Resonance Imaging: Principles and Applications", Williams and Wilkins, Baltimore, 1986.
Kennedy et al., J. Appl. Chem. 1958, 8, 459-464.
Kies in "Nutritional Bioavailability of Manganese", Kies, Ed., American Chemical Society, Washington, DC, 1987, Ch. 1, pp. 1-8.
Kies et al., in "Nutritional Bioavailability of Manganese", Kies, Ed., American Chemical Society, Washington, DC, 1987, Ch. 13, pp. 136-145.
Leonard et al., J. App. Polymer Sci. 1961, vol. V, 157-162.
Leonard et al., J. of Polymer Sci. 1961, 55, 799-810.
Maddaiah et al., Proc. Soc. Exp. Biol. Med. 1964, 115, 391-393.
Marvel et al., J. of Polymer Sci. 1952, vol VIII, 495-502.
Morris, E.R., in "Phytic Acid: Chemistry and Application", Graf, Ed., Pilatus Press, Minneapolis, MN, 1986, Ch. 4, pp. 57-76.
Pilgrimm, H., Chemical Abstracts 1990, 112, No. 51778y.
Reddy et al., "Phytates in Cereals and Legumes", CRC Press, Inc., Boca Raton, FL, 1989, Ch. 7, pp. 57-70.
Reddy et al., "Phytates in Cereals and Legumes", CRC Press, Inc., Boca Raton, FL, 1989, Ch. 9, pp. 81-110.
Sander et al., J. Macromol. Sci., Rev. Macromol. Chem. 1968, 2, 57-72.
Schroeder et al., J. of Polymer Sci. 1950, vol. XLVII, 417-433.
Thomson et al., J. Lab. and Clin. Med. 1971, 78, 642-655.
Vohra et al., Proc. Soc. Exp. Biol. Med. 1965, 120, 447-449.

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