Phosphorylated glyoxalase I and its use

Details Phosphorylated glyoxalase I and its use Phosphorylated glyoxalase I and its use

2007-04-03

2007-04-03

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Lyase

C424S094100, C424S094500, C435S183000, C530S350000, C530S352000

Reexamination Certificate

active

10630451

ABSTRACT:
The present invention relates to a phosphorylated form of mammalian glyoxalase I. The present invention relates further to the use of phosphorylated mammalian glyoxalase I to modulate MG-modification of proteins (AGE formation) and consequent cell death, especially upon stress such as oxidative stress, or upon TNF treatment.

REFERENCES:
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