Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Phosphoproteins – e.g. – phosvitin – vitellogenin – etc.
Patent
1995-06-07
2000-11-21
Mertz, Prema
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Phosphoproteins, e.g., phosvitin, vitellogenin, etc.
435 6951, 435 697, 435 712, 435471, 435325, 4352523, 4353201, 536 234, 536 235, 536 2352, 424 141, 424 149, C07K 1456, C07K 14565, C12N 1562
Patent
active
06150503&
ABSTRACT:
Modified proteins, modified interferons .alpha.'s and .beta.'s, phosphorylated modified proteins and DNA sequences encoding the above, applications and uses thereof. Modified phosphorylated Hu-IFN-.alpha.-like proteins are provided which carry an identifiable label such as a radio-label. Corresponding phosphorylatable Hu-IFN-.alpha.-like proteins which contain a putative phosphorylation site. DNA sequences which encode a Hu-IFN-.alpha.-like protein and contain a sequence encoding a putative phosphorylatable site. Appropriate expression vectors are used to transform compatible host cells of various microorganisms, such as E. coli. Numerous uses for the phosphorylated proteins are disclosed.
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Arnold Beth E.
Mertz Prema
Pestka Biomedical Laboratories, Inc.
Vincent Matthew P.
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