Phosphorylated cyclic lipopeptide

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 9, 530317, 530323, 435 711, 435 713, 435939, 930270, 930DIG536, A61K 3702, C07K 754

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active

051984210

ABSTRACT:
There is disclosed a monophosphorylated cyclic lipopeptide compound obtained by biophosphorylating a cyclic lipopeptide related to echinocandins and having a peptide skeleton bearing several hydroxy groups wherein in the phosphorylated cyclic lipopeptide, the phosphate group is attached to the hydroxy group of the 4-hydroxyproline component of the lipopeptide. The compounds are useful for the control of fungi and parasites.

REFERENCES:
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H. Holland, et al., Microbial hydroxylation of steroids.5.Metabolism of androst-5-ene-3,17-dione and related compounds by Rhizopus arrhizus ATCC 11145, Can. J. Chem., vol. 57, 1979, pp. 436-440.
H. Holland, et al., Microbial hydroxylation of steroids.6.Hydroxylation of C-6-substituted androst-4-ene-3,17-diones by Rhizopus arrhizua ATCC 11145 Can. J. Chem., vol. 57, 1979, pp. 1585-1587.

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