Phosphorus containing derivatives of epipodophyllotoxin

Details Phosphorus containing derivatives of epipodophyllotoxin Phosphorus containing derivatives of epipodophyllotoxin

1987-01-08

1990-04-10

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 41, 536 181, 536117, C07H 1500, C07H 1700

Patent

active

049162179

ABSTRACT:
Etoposide-3',4'-quinone is converted into a phosphorane or phosphate ester by reaction with an organic phosphine or phosphite. The resulting phosphoranes and phosphates have anti-tumor activity in animals.

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patent: 4757138 (1988-07-01), Fujii et al.

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