Phosphorous-containing HMG-CoA reductase inhibitors, new interme

Details Phosphorous-containing HMG-CoA reductase inhibitors, new interme Phosphorous-containing HMG-CoA reductase inhibitors, new interme

1989-12-01

1991-05-21

Shaver, Paul F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Silicon containing

C07F 708

Patent

active

050177168

ABSTRACT:
Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have the structure ##STR1## including salts thereof, wherein R is OH, lower alkoxy or lower alkyl; R.sup.x is H or alkyl;

REFERENCES:
patent: 3840577 (1974-08-01), Kodama et al.
patent: 3912774 (1975-10-01), Kotzcth et al.
patent: 4093641 (1978-06-01), Plueddemann
patent: 4804770 (1989-02-01), Karanewsky

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