Phosphorotriamides as urease inhibitors

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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424211, 424218, 424220, A61K 3166

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active

042423252

ABSTRACT:
Certain phosphorotriamides of the formula ##STR1## wherein R is hydrogen, phenyl, 4-nitrophenyl, 4-aminophenyl, 4-cyanophenyl or 3-trifluromethylphenyl are useful as inhibitors of the enzyme urease.

REFERENCES:
The Enzymes, vol. 1, Part 2, pp. 882-885, 1951 Academic Press, Inc., Pub. New York.
The Chemistry and Technology of Enzymes, pp. 119-120 Tauber, John Wiley & Sons, Inc. New York
Inorganic Synthesis, 6:108-111, Klement et al.
Bull. Chem. Soc., Japan 46:183 (1973).

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