Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1977-02-15
1978-09-12
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
424200, 424216, 424219, A01N 900, A01N 936
Patent
active
041138643
ABSTRACT:
Phosphorothiolates represented by the formula, ##STR1## wherein R is an alkyl; A is an alkyl, haloalkyl, alkenyl, alkinyl, alkylthioalkyl, phenylthioalkyl, phthalimidoalkyl or phenylalkyl; X is hydrogen, a halogen or an alkyl; and n is an integer of 1 to 5, are obtained by (1) reacting sodium or potassium hydrosulfide with a compound represented by the formula, ##STR2## WHEREIN R, X and n have the same significances as mentioned above, to prepare a thiophosphate represented by the formula, ##STR3## wherein R, X and n have the same significances as mentioned above; and M is an alkali metal, and then (2) reacting said thiophosphate with a halide represented by the formula,
REFERENCES:
patent: 3641221 (1972-07-01), Schrader et al.
patent: 3839511 (1974-10-01), Kishino et al.
patent: 4028438 (1977-06-01), Tsuchiya et al.
Fujimoto Keimei
Kimura Akio
Mukai Kunio
Ogawa Taizo
Okuno Yositosi
Robinson Allen J.
Sumitomo Chemical Company Limited
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