Phosphoramidite nucleoside analogs

Details Phosphoramidite nucleoside analogs Phosphoramidite nucleoside analogs

2008-08-29

2011-12-27

Riley, Jezia (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S025300, C536S025400, C514S04400A, C435S007100

Reexamination Certificate

active

08084589

ABSTRACT:
Described are phosphoramidite nucleoside analog monomers, precursors thereof, and oligonucleotides including one or more of the monomers. The monomers can be used during automated synthesis of oligonucleotide derivatives, and allow for incorporation of one or several reporter groups, organic molecules, bio-molecules, small molecules or other chemical groups at the internucleoside phosphotriesters. Oligonucleotides including the monomers have a number of uses in therapeutic, diagnostic, and research applications.

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