Phosphoramidate derivatives

Details Phosphoramidate derivatives Phosphoramidate derivatives

1996-12-31

1999-01-26

Huff, Sheela

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

546 21, 562 10, 514 89, 514 91, 514 95, 514121, A61K 39395

Patent

active

058635360

ABSTRACT:
The present invention includes phosphoramidate derivatives, compositions containing the same, and methods of using them as NAALADase inhibitors, particularly for the treatment of glutamate abnormalities and associated nervous tissue insult in a animal and for treatment of prostate disease and prostate cancer by inhibition of NAALADase enzyme.

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