Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-03-11
1999-02-23
Marschel, Ardin H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 5, 435 6, 536 231, 536 243, 536 253, 536 2532, 514 1, 514 44, C07H 1900, C12Q 168, A01N 6100
Patent
active
058745530
ABSTRACT:
Novel oligonucleotide analogs of the formula (I) are described, ##STR1## in which A, B, D, G, L, P, Q, Q', R.sup.5, R.sup.6, X, Y, Z and n are as defined in the description, which have useful physical, biological and pharmacological properties, as well as a process for their preparation. Their application relates to use as inhibitors of gene expression (antisense oligonucleotides, ribozymes, sense oligonucleotides and triplex-forming oligonucleotides), as probes for the detection of nucleic acids and as auxiliaries in molecular biology.
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Breipohl Gerhard
Peyman Anuschirwan
Uhlmann Eugen
Wallmeier Holger
Hoechst Aktiengesellschaft
Marschel Ardin H.
Riley Jezia
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